PROVE Network
dynamic realm
explore a comprehensive body of research created by the PROtective VEntilation (PROVE) Network, comprising 20 RCTs and 11 observational studies in ventilation, along with insights from 6 harmonized and pooled databases
delve into 7 studies on closed–loop ventilation, examine findings from 3 Delphi consensus processes covering various aspects of respiratory support, and stay informed on 3 large–scale COVID–19 projects
additionally, explore preclinical studies focused on lung protection and cutting–edge projects in the realm of artificial intelligence
history
the PROVE Network, established in 2014 by Prof. Paolo Pelosi, Prof. Marcelo Gama de Abreu, Prof. Marcus Schultz, Dr. Sabrine Hemmes, and Prof. Ary Serpa Neto, conducts impactful multicenter clinical studies in ventilation
our research explores novel strategies to enhance patient care and safety in operating rooms (OR) and intensive care units (ICU)
led by esteemed professionals, the network comprises dedicated sections for randomized clinical trials (RCTs), observational studies, and secondary/meta–canalyses; Dr. Chiara Robba and Dr. Denise Battaglini lead the RCT section, Dr. Sabrine Hemmes and Dr. Lorenzo Ball oversee observational studies, Prof. Ary Serpa Neto, supported by Dr. Guido Mazzinari and Dr. David van Meenen, heads the section for secondary/meta–analyses, Prof. Frederique Paulus supervises the COVID–19 projects, Dr. Laura Buiteman coordinates the studies of closed-loop ventilation, and Dr. Prashant Nasa guides Delphi's
in addition, the PROVE Network is also involved in AI and preclinical projects at various specialized laboratories worldwide, and this work is managed by Dr. Robert Huhle, Dr. Martin Scharffenberg and Dr. Jakob Wittenstein
true worldwide collaborations
discover our global network of research centers across 6 continents, actively engaged in groundbreaking clinical investigations and innovative preclinical studies
join our collaborative spirit that transcends borders, fueling continuous advancements
high–quality research
the PROVE Network performs high–quality research and initiates research projects based on ideas from researchers within and from outside the network
in every project an original hypothesis is tested, using an adequate study design and a sufficient number of patients, and PROVE Network–initiated studies follow a strict action plan
published work
PROVE Network investigators publish their work in peer–reviewed journals
an overview of pubslished work can be found at PubMed
more than 20 academic theses have been written and defended; in the coming 2 years, 14 additional theses will be completed
in the legacy of Paolo Pelosi
we greatly miss our mentor, colleague, and close friend, Paolo, who was a real mastermind in uniting colleagues all over the world for the sake of improving the care of patients; in the legacy of Paolo, we will continue his mission by bringing people together, working together, and will not forget the joy and fun while doing this all
